Autoimmune disorder causing vasculitis principally in eyes, mucous membranes, skin, but also in many other organs
Diagnosed most commonly in Middle East and Asia around old Silk Road trading route
Main systemic manifestations: recurrent painful mouth and genital ulcers, arthritis, meningoencephalitis
Main ophthalmic manifestations: anterior uveitis often with hypopyon, retinal vasculitis, vitreous cells, optic neuropathy, papilledema from dural venous sinus thrombosis
Refer urgently to ophthalmologist any patient with diagnosis of Behçet disease who has newly blurred vision
Refer non-urgently any patient without visual symptoms in whom Behçet disease is suspected in order to help confirm diagnosis and detect manifestations of mild ophthalmic involvement
