Retinal Vasculitis

  • White cuff around retinal vessels that looks like frosting ("vascular sheathing")
  • Made up of perivascular lymphocytes
  • Caused by vascular inflammation ("vasculitis") associated with sarcoidosis, Behçet disease, and other autoimmune conditions
  • Retinal vessel (usually vein) segmentally surrounded by thin white cuff that varies in thickness along vessel
  • Silver-wiring in chronic hypertension, where arterial wall is so thickened that red blood column is obliterated, BUT...in vasculitis you should see blood column unless vessel is occluded
  • Attenuation of retinal nerve fiber layer from optic neuropathy
  • Old retinal artery occlusion
  • Interpret this finding as sign of retinal vascular inflammation and think of diseases that do this
  • Refer to ophthalmologist non-urgently unless symptoms are new and marked
  • Vasculitis may be restricted to eye, but more commonly it affects vessels in other tissues, so...
  • Patient needs systemic work-up
  • In retina, vessels can become occluded and cause blindness unless treatment undertaken