Thrombocytopenia

  • Low platelet count from many different causes
  • Most common ophthalmic manifestion: retinal hemorrhages; occur commonly when platelet count falls below 20,000/mm3
  • Patients have blurred vision if retinal hemorrhage located at fovea or notice dark spot if hemorrhage is near fovea
  • Hemorrhages may be...
  • Dot-blot within retina
  • Flame-shaped in retinal surface nerve fiber layer
  • Bubble-shaped or boat-shaped between retina and vitreous
  • White-centered ("Roth spots")
  • Refer only if patient complains of visual symptoms
  • Retinal hemorrhages resolve spontaneously within weeks, but may recur if platelet count remains low
  • Vision usually recovers to normal as hemorrhage clears, but foveal hemorrhages may leave behind slightly distorted vision
  • Transfusions to raise platelet count necessary only if visual loss is severe and persistent