Strabismus

  • Ocular misalignment, especially with onset at birth or in childhood
  • May reflect disorder of brain, cranial nerves, neuromuscular junction, or extraocular muscles
  • Diagnosis based on history, pattern of misalignment, and associated findings
  • Patient reports diplopia that disappears upon covering either eye, but remember that...
  • Children rarely report diplopia because they suppress image from deviating eye
  • One eye appears not to be fixating stationary viewed object
  • One eye appears not to be tracking moving viewed object
  • One eye appears not to be moving fully in one or more gaze directions
  • Covering one eye ("cover test") elicits fixational movement by other eye
  • Wide nasal bridge gives false impression of convergent strabismus ("pseudostrabismus")
  • Displacement of an eye by orbital tumor or trauma may give false impression of misalignment
  • Ptosis or lid retraction may give false impression of misalignment
  • Confirm strabismus by performing cover test and eliciting fixational eye movement, or...
  • Noting if diplopia disappears as patient covers either eye
  • Understand that strabismus may be hard to diagnose if misalignment is small, patient does not report diplopia, is uncooperative, or cannot properly execute fixation movement on cover test, so...
  • If you are not sure of your test results or patient reports diplopia...
  • Refer with urgency that depends on how recently strabismus was noted and on accompanying pertinent findings, because...
  • Brain aneurysm or other life-threatening conditions could be present
  • Strabismus in early childhood often accompanied by amblyopia, which must be promptly treated to prevent persistent vision loss
  • Treatment of strabismus depends on underlying cause
  • Causes in young children are excessive convergence of brain stem origin ("congenital esotropia"), esotropia of hyperopia ("accommodative esotropia"), impaired vision ("sensory strabismus"), and excessive idiopathic divergence ("exotropia")
  • Causes in adults are internuclear ophthalmoplegia, skew deviation, cranial nerve palsies, myasthenia gravis, extraocular muscle inflammation, and orbital trauma
  • Most urgent diagnosis is third cranial nerve palsy because could be caused by brain aneurysm with imminent rupture and death