Iris Melanoma

  • Brown pigmented mass on iris
  • Low-grade malignancy
  • Not associated with melanoma of skin or other tissues
  • Iris freckle—layer of melanocytes present at birth and not enlarging
  • Iris nevus—mounds of melanocytes present at birth and not enlarging very much
  • Lisch nodule—small light brown non-enlarging hamartomas found in neurofibromatosis type 1
  • Granuloma of sarcoidosis—inflammatory mound located at iris margin or mid-iris region
  • Refer non-urgently if patient has new visual symptoms or thinks lesion new or growing
  • Lesion suspicious for melanoma will be biopsied
  • Metastasis very rare unless lesion extends into ciliary body