Tamsulosin

  • Selective alpha-1A antagonist used to treat symptoms in benign prostatic hypertrophy
  • Most common ophthalmic side effect:  floppy iris syndrome
  • Dome-shaped anterior displacement of iris
  • Prolapse of iris during cataract surgery, requiring special measures to prevent surgical complications
  • Occurs in up to 60% of patients
  • Discontinue medication within week of anticipated intraocular surgery
  • Floppy iris syndrome must be anticipated by cataract surgeon to avoid complications
  • Special maneuvers usually allow safe lens extraction