Scleritis

  • Focal or diffuse inflammation of sclera
  • Isolated to eye or associated with systemic autoimmune condition such as rheumatoid arthritis or granulomatous polyangiitis (formerly Wegener granulomatosis)
  • May lead to perforation of sclera and loss of eye
  • Episcleritis, anterior uveitis, conjunctivitis, BUT...
  • Episcleritis causes relatively little pain and no scleral thinning
  • Anterior uveitis causes diffuse or ciliary engorgement of conjunctival vessels, less pain, and no scleral thinning
  • Conjunctivitis causes diffuse engorgement of conjunctival vessels, no pain, and much more discharge
  • Refer urgently to ophthalmologist
  • Diagnosis includes search for underlying systemic condition
  • Treatment involves systemic corticosteroids or other immune-modulating agents
  • Threatened ocular perforation may require surgical patch grafts
  • Outcome depends on type and aggressiveness of underlying condition and patient tolerance of medication used to treat