Allergic Conjunctivitis

  • Inflamed conjunctiva and lids as part of reaction to systemic allergen (usually pollens or grasses)
  • Usually peaks in Spring or Fall
  • Often accompanied by upper respiratory tract symptoms, but may be most bothersome—or only—manifestation
  • Itchy eyes—usually both of them
  • Swollen lids
  • Diffusely red (hyperemic) conjunctiva
  • Mild watery—sometimes mucoid—discharge
  • Preserved vision
  • Often upper respiratory allergic manifestations
  • Prescribe systemic antihistamines
  • If they do not work, prescribe from these topical choices:
    • Vasoconstrictors:
      • inexpensive over-the counter agents
      • include antazoline phosphate 0.05%, naphazoline HCl 0.05%, oxymetazoline HCl, tetrahydrozoline HCl 0.05%, and phenylephrine 0.12%
    • H-1 receptor antagonists:
      • more effective than vasoconstrictors, but more expensive
      • include pheniramine maleate 0.3% (Naphcon), emedastine (Emadine), and levocabastine HCl 0.05% (Livostin)
    • Nonsteroidal anti-inflammatory agents:
      • used in combination with other topical agents
      • include ketorolac tromethamine 0.5% (Acular) and ketotifen 0.025% (Zaditor)
    • Mast cell stabilizers:
      • include cromolyn sodium 4% (Crolom), nedocromil 2% (Alocril), pemilorast 0.1% (Alamast), and lodoxamide tromethamine 0.1% (Alomide)
    • Combined H-1 receptor antagonist and mast cell stabilizers
      • more effective than mast cell stabilizers alone
      • include olopatadine hydrochloride 0.1% (Patanol), optivar, and elestan
  • Systemic medications do not always eliminate symptoms adequately
  • Topical medications, with or without systemic medications, usually provide adequate relief; if not, condition particularly fierce or diagnosis wrong, so refer to ophthalmologist
  • Symptoms usually decrease spontaneously when allergen level falls