Ptosis

  • Droopy upper lid
  • Many causes, including congenital levator muscle weakness, trauma or inflammation of upper lid, myasthenia gravis, third nerve palsy, Horner syndrome, aging weakness of levator tendon
  • Clinical features may allow distinction of one cause of ptosis from another, for example...
  • Congenital ptosis is present from birth, has inelastic lid tissue that does not allow normal elevation or depression
  • Traumatic ptosis follows cuts and blows to upper lid
  • Contact lens-induced ptosis follows long-term contact lens wear, especially with hard or gas permeable lenses and with history of lid inflammation
  • Inflammatory ptosis follows infections and allergies of lid skin, conjunctiva, and orbit
  • Myasthenic ptosis fluctuates and is often accompanied by diplopia and weakness of limbs, speech, chewing, and swallowing
  • Third nerve palsy ptosis comes with diplopia, reduced eye movements, ocular misalignment, and larger pupil on side of ptosis
  • Horner syndrome ptosis is typically mild and comes with smaller pupil on side of ptosis ("anisocoria")
  • Aponeurotic (aging) ptosis is slowly progressive, mild, symmetric in two eyes, and displays elevated upper lid crease 

  • Blepharospasm, or contraction of orbicularis oculi muscle, BUT...blepharospasm is usually intermittent, lowers brow, and raises lower lid
  • Hemifacial spasm, like blepharospasm, except unilateral
  • Post-paretic facial contracture, a fixed abnormality that follows facial palsy, BUT...also raises lower lid
  • Blepharochalasis (or dermatochalasis), redundant skin of upper lid caused by aging or inflammatory stretching, BUT...redundant skin can be lifted to reveal normal level of upper lid margin
  • Upper lid swelling from inflammation or tumor, BUT...lid is usually deformed and sensitive to touch
  • Upward displacement of eye, giving false impression that ipsilateral upper lid is lower, BUT...patient will usually have diplopia or proptosis or enophthalmos
  • Lid retraction, giving false impression that contralateral upper lid is lower, BUT...lid retraction usually accompanied by lid lag 

  • Try to distinguish between ptosis and mimickers, and...
  • Try to distinguish between isolated ptosis and...
  • Ptosis with larger pupil on same side (possible third nerve palsy), or...
  • Ptosis with smaller pupil on same side (possible Horner syndrome)
  • Third nerve palsy and Horner syndrome are urgent considerations
  • Everything else can wait