Pseudoxanthoma Elasticum

  • Autosomal recessive disorder causing degeneration of elastic tissue, especially in skin, blood vessels, eyes
  • Causes tears in Bruch’s membrane, which lies between retina and choroid
  • New blood vessels sometimes develop under fovea,¬†bleed, and blind
  • Refer all patients with pseudoxanthoma elasticum for periodic ophthalmologic examination to detect new blood vessels
  • Warn patients to consult ophthalmologist immediately should they notice sudden blurring or warping of vision
  • Advise wearing protective glasses and avoiding contact sports because trauma can worsen condition
  • Treatments used in wet age-related macular degeneration often prevent severe vision loss