- Malformed trabecular meshwork at birth causes elevated intraocular pressure, enlarged eye, cloudy cornea, tearing
- Surgery to repair meshwork or bypass it and lower intraocular pressure must be prompt to prevent permanent vision loss.
- Fussy baby, cloudy cornea, tearing, enlarged eye ("buphthalmos", or ox eye)
- May be monocular or binocular
- Elevated intraocular pressure can be measured
- Usually not associated with other congenital anomalies
- Congenital corneal dysplasias or systemic metabolic disorders causing cloudy corneas, but...
- They usually do not have elevated intraocular pressure, large eye, or tearing
- Refer urgently any baby with cloudy cornea