1. History
  2. Exam
  3. Photos
  4. Diagnosis
  5. Teaching Points
  6. Comments

Case 34 Diagnosis

Stargardt disease

Differential Diagnosis

  • Fundus albipunctatus: a form of congenital stationary night blindness with white dots scattered throughout the retina, sparing the macula.
  • Retinitis punctata albescens: a variant of retinitis pigmentosa with numerous white dots in the deep retina and arteriolar narrowing
  • Fleck retina of Kandori: large, irregular yellow flecks sparing the macula
  • Familial drusen: usually dominant inheritance. Central vision remains good as long as drusen are discrete and not involving the fovea.
  • Sorsby macular dystrophy: dominant inheritance. Macular lesions lead to bilateral subfoveal choroidal neovascularization.
  • Cone dystrophy: abnormal photopic electroretinogram
  • X-linked juvenile retinoschisis: X-linked inheritance. Negative electroretinogram.
  • Best vitelliform dystrophy: distinctive yellow “egg yolk” lesion in the macula that later breaks down into a “scrambled egg” lesion. Usually retain good visual acuity.
  • Chloroquinine maculopathy: bulls-eye maculopathy in patients taking the drug, but without surrounding pisciform flecks
  • Age-related macular degeneration: usually symptoms begin much later in life than with Stargardt disease
Last Modified: Friday, 27-Jun-2008 11:53:34 EDT