1. History
  2. Exam
  3. Photos
  4. Diagnosis
  5. Teaching Points

Case 105 Teaching Points

  • Mold frequently found in decaying vegetable matter
  • People at greatest risk of ocular infections are intravenous drug abusers and those with a variety of immune modulating diseases, endocarditis, and cancer patients
  • Aspergillus is the second most common fungus to infect the retina and choroid after C. albicans
  • A. fumigatus and A. flavus are the most commonly isolated species from patients with intraocular infection
  • Serologic tests and blood cultures may be negative despite disseminated infection
  • Characterized by yellow subretinal and retinal infiltrates
  • Endophthalmitis frequently characterized by rapid, severe vision loss, intense inflammation, and retinal hemorrhage
  • Infection usually occurs in the posterior pole
  • Macular lesions common
  • Invasion of vessels with production of thrombosis and infarction is a characteristic feature
  • Occlusion of choroidal vessels can lead to exudative retinal detachment
  • Occlusion of retinal vessels can lead to retinal necrosis


Ryan SJ. Retina, 4th ed., Vol 3. Philadelphia:Mosby, 2006, pp 1684-1692.

Last Modified: Tuesday, 27-May-2008 14:40:59 EDT