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Areas of Research - Clinical Research

Age-related Macular Degeneration (see also Clinical Trials)

Mark W. Johnson, M.D.

Pharmacologic and laser treatment of age-related macular degeneration

David C. Musch, Ph.D., M.P.H. Consultation to and Data & Safety Monitoring Board membership for studies of pharmacologic and laser treatments of ARMD

Cornea and External Disease (see also Clinical Trials)

Shahzad I. Mian, M.D. Femtosecond assisted posterior lamellar keratoplasty; Outcomes of keratoprosthesis; clinical studies in refractive surgery techniques and outcomes; ocular graft versus host disease; dry eye disease
H. Kaz Soong, M.D. Excimer laser studies (LASIK and PRK); laser treatments for ocular defects
Alan Sugar, M.D. Principal Investigator for excimer laser studies (LASIK and PRK); laser treatments for ocular defects
Epidemiology
David C. Musch, Ph.D., M.P.H. Epidemiological research (both observational and interventional) on common ophthalmic conditions, with a particular focus on glaucoma treatment, corneal transplantation outcomes, prevention and treatment of age-related macular degeneration, studies of oculoplastics surgical procedures, and quality of life studies in children and adults with strabismus and ptosis. Advisor and consultant to multiple clinical research studies in the Department.
Eye Plastic, Orbital & Facial Cosmetic Surgery
Bartley R. Frueh, M.D. Studies in ocular muscle physiology, ptosis, blepharospasm, lid retraction, and hydroxyapetite orbital implants.
Christine C. Nelson, M.D. Histological studies of the muscles of the eyelids; oncology of the lid and orbit

Glaucoma (see also Clinical Trials)

Terry J. Bergstrom, M.D. Principle Investigator of the Ocular Hypertension Treatment Study
Paul R. Lichter, M.D. Clinical and molecular genetics of glaucoma; initial management of glaucoma and the impact of glaucoma treatment on quality of life; Chairman of the Collaborative Initial Glaucoma Treatment Study; medical applications of ultrafast lasers
Sayoko E. Moroi, M.D., Ph.D. Glaucoma, inherited glaucomas, clinical trials (co-investigator on the Ocular Hypertension Treatment Study), complementary and alternative medicine, medical compliance, glaucoma treatment and surgery outcomes
David C. Musch, Ph.D., M.P.H. Analysis of visual field changes over time in glaucoma patients, and Coordinating Center Director for the Collaborative Initial Glaucoma Treatment Study
Neuro-Ophthalmology (see also Clinical Trials)
Wayne T. Cornblath, M.D. Clinical studies in optic neuritis, optic neuropathy, pseudotumor cerebri, myasthenia gravis, giant cell arteritis, blepharospasm, and thyroid eye disease
Jonathan D. Trobe, M.D. Visual fields; visuospatial manifestations of neurodegenerative disorders; clinical studies of optic neuritis and optic neuropathy; optic nerve diseases

Pediatric Ophthalmology (see also Clinical Trials)

Steven M. Archer, M.D. Development of vision in infants
Monte A. Del Monte, M.D. Tissue culture and cell biology of ocular tissue; basic studies on the mechanism and treatment of diabetic retinopathy; ocular inborn errors in metabolism; biochemical genetics; surgical and non-surgical therapy for strabismus, amblyopia, congenital cataract, pediatric glaucoma, and lacrimal duct abnormalities in infants and children
Maya Eibschitz, M.D.

Cataract surgery and intraocular lens placement in infants and children, pediatric glaucoma, diagnosis and treatment of amblyopia and strabismus

Erika Levin, M.D. Principal investigator of Pediatric Eye Disease Investigator Group; pediatric vision screening; treatment of strabismus (eye misalignement) in children and adults, amblyopia (lazy eye), tear duct blockages, and cataracts; diagnosis of inherited eye diseases in children

Retina (see also Clinical Trials)

John R. Heckenlively, M.D. Investigation of vascular loss in RP; linkage analysis to find disease-causing genes; study involving 20 centers worldwide to identify genes underlying macular telangiectasia; investigation of electrophysiological changes in patients with AMD and related search for new causative retinal degeneation genes. Advisor to ophthalmology resident projects on cone degeneration associated with aging; the role of anti-oxidant vitamins in slowing panretinal degenerations; and the role of inflammation in retinal edema and retinal degenerations. PI of project that develops mouse models of human ocular diseases in which over 110 different models have been found to date for diseases such as retinitis pigmentosa, macular degeneration, choroidal neovascularization, glaucoma, cataract. One the phenotype is determined, the gene is found through linkage and cloning.
Naheed W. Khan, Ph.D. Visual electrophysiology of retinal degenerative diseases and clinical electrodiagnostics
Andrew K. Vine, M.D. Principal Investigator for the Collaborative Ocular Melanoma Study; Principal Investigator for the Protein Kinase C Inhibitor Study; pharmacological treatment of diabetic retinopathy and macular edema; homocysteine blood levels and vascular disease of the eye; ocular oncology
David N. Zacks, M.D., Ph.D.

Mechanisms of retinal cell death during retinal diseases such as retinal detachments, age-related macular degeneration and ocular inflammatory disease

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