Clinical Research

Age-related Macular Degeneration

(see also Clinical Trials)

Cornea and External Disease

(see also Clinical Trials)

  • Shahzad I. Mian, M.D.
    Femtosecond assisted posterior lamellar keratoplasty; Outcomes of keratoprosthesis; clinical studies in refractive surgery techniques and outcomes; ocular graft versus host disease; dry eye disease
  • Roni M. Shtein, M.D.
    High risk cornea transplantation; clinical confocal microscopy; dry eye and ocular surface disease; corneal immunology; refractive surgery techniques and outcomes
  • H. Kaz Soong, M.D.
    Excimer laser studies (LASIK and PRK); laser treatments for ocular defects
  • Alan Sugar, M.D.
    Principal Investigator for excimer laser studies (LASIK and PRK); laser treatments for ocular defects

Diabetes and Diabetic Retinopathy


  • David C. Musch, Ph.D., M.P.H.
    Epidemiological research (both observational and interventional) on common ophthalmic conditions, with a particular focus on glaucoma treatment, corneal transplantation outcomes, prevention and treatment of age-related macular degeneration, studies of oculoplastics surgical procedures, and quality of life studies in children and adults with strabismus and ptosis. Advisor and consultant to multiple clinical research studies in the Department.

Eye Plastic, Orbital & Facial Cosmetic Surgery


(see also Clinical Trials)

  • Terry J. Bergstrom, M.D.
    Principle Investigator of the Ocular Hypertension Treatment Study
  • Paul R. Lichter, M.D.
    Clinical and molecular genetics of glaucoma; initial management of glaucoma and the impact of glaucoma treatment on quality of life; Chairman of the Collaborative Initial Glaucoma Treatment Study; medical applications of ultrafast lasers
  • Sayoko E. Moroi, M.D., Ph.D.
    Glaucoma, inherited glaucomas, clinical trials (co-investigator on the Ocular Hypertension Treatment Study), complementary and alternative medicine, medical compliance, glaucoma treatment and surgery outcomes
  • David C. Musch, Ph.D., M.P.H.
    Analysis of visual field changes over time in glaucoma patients, and Coordinating Center Director for the Collaborative Initial Glaucoma Treatment Study
  • Joshua D. Stein, M.D., M.S.
    Health services research, patterns of eye care in the United States, outcomes of glaucoma surgery, quality of life of patients with ocular disorders

Graves’ Disease and Graves’ Ophthalmopathy

  • Raymond S. Douglas, M.D., Ph.D.
    Immunologic mechanisms of thyroid eye disease, with a focus on understanding fundamental molecular processes and applying these findings to clinical trials.
  • Terry J. Smith, M.D.
    Translational studies examining the potential for identifying biomarkers of Graves’ ophthalmopathy and developing small molecule and antibody-based therapies for interrupting the insulin-line growth factor 1 receptors.


(see also Clinical Trials)

  • Wayne T. Cornblath, M.D.
    Clinical studies in optic neuritis, optic neuropathy, pseudotumor cerebri, myasthenia gravis, giant cell arteritis, blepharospasm, and thyroid eye disease
  • Jonathan D. Trobe, M.D.
    Visual fields; visuospatial manifestations of neurodegenerative disorders; clinical studies of optic neuritis and optic neuropathy; optic nerve diseases

Ocular Oncology

(see also Clinical Trials)

  • Hakan Demirci, M.D.
    Translational approach to early diagnosis of eye cancers, targeted treatment of intraocular tumors, and prevention of metastasis

Pediatric Ophthalmology

(see also Clinical Trials)

  • Steven M. Archer, M.D.
    Development of vision in infants
  • Monte A. Del Monte, M.D.
    Tissue culture and cell biology of ocular tissue; basic studies on the mechanism and treatment of diabetic retinopathy; ocular inborn errors in metabolism; biochemical genetics; surgical and non-surgical therapy for strabismus, amblyopia, congenital cataract, pediatric glaucoma, and lacrimal duct abnormalities in infants and children


(see also Clinical Trials)

  • Robin Ali Ph.D., FMedSci
    Clinical trials of gene and cell therapy for treatment of retinal degeneration
  • Kari Branham, M.S., C.G.C.
    Genetic counselor; coordination of genetic testing for multiple genetic studies; coordination of the genetic screening of patients in the X-linked Retinitis Pigmentosa and the Age-Related Macular Degeneration (AMD) Genetic Study Groups. For the AMD Study, coordination of several genetic screening efforts including individual gene association studies, genome-wide association studies, genotype-phenotype correlation studies, and medical sequencing.
  • John R. Heckenlively, M.D.
    Investigation of vascular loss in RP; linkage analysis to find disease-causing genes; study involving 20 centers worldwide to identify genes underlying macular telangiectasia; investigation of electrophysiological changes in patients with AMD and related search for new causative retinal degeneation genes. Advisor to ophthalmology resident projects on cone degeneration associated with aging; the role of anti-oxidant vitamins in slowing panretinal degenerations; and the role of inflammation in retinal edema and retinal degenerations. PI of project that develops mouse models of human ocular diseases in which over 110 different models have been found to date for diseases such as retinitis pigmentosa, macular degeneration, choroidal neovascularization, glaucoma, cataract. One the phenotype is determined, the gene is found through linkage and cloning.
  • K. Thiran Jayasundera, M.D.
    Determining phenotype-genotype correlations and predictive value of metabolic and functional testing in Stargardt disease.
  • Naheed Wali Khan, Ph.D.
    Visual electrophysiology of retinal degenerative diseases and clinical electrodiagnostics
  • Yannis M. Paulus, M.D.  
    Development of novel retinal imaging systems and therapeutic techniques and technologies, including photoacoustic imaging, molecular imaging, restorative retinal laser therapy, and surgical techniques.
  • David N. Zacks, M.D., Ph.D.
    Mechanisms of retinal cell death during retinal diseases such as retinal detachments, age-related macular degeneration and ocular inflammatory disease
Last Modified: Friday, 10-Feb-2017 13:19:03 EST