| Biochemistry, Pharmacology, and Molecular Biology | |
| Monte A. Del Monte, M.D. |
Basic studies on the etiology and treatment of diabetic retinopathy, mechanisms of hereditary eye disease |
| Susan G. Elner, M.D. | Inflammatory processes of the retina and retinal pigment epithelium |
| Victor M. Elner, M.D., Ph.D. | Molecular targets of retinal inflammation and degeneration |
| Hemant Khanna, Ph.D. | Protein trafficking in photoreceptors in transport-related retinal dystrophy |
| Sayoko E. Moroi, M.D., Ph.D. | Molecular pharmacology of glaucoma medications; aqueous humor dynamics; wound healing |
| Terry J. Smith, M.D. | Molecular mechanisms underlying the pathogenesis of thyroid-associated ophthalmopathy, extracellular matrix, cell signaling and gene expression. |
| Debra A. Thompson, Ph.D. | Molecular studies of retinal pigment epithelium function and regulation |
| Dongli Yang, M.D., Ph.D. | Molecular mechanisms of retinal inflammation and degeneration |
| David N. Zacks, M.D., Ph.D. | Mechanisms of retinal cell death during retinal diseases such as retinal detachments, age-related macular degeneration and ocular inflammatory disease |
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Cell and Developmental Biology |
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| Monte A. Del Monte, M.D. | Cell biology of ocular tissue, especially human retinal pigment epithelium , tissue culture models of ocular diseases |
| Victor M. Elner, M.D., Ph.D. | Cell-cell receptor and cytokine-mediated communication; inflammatory and scarring mechanisms; intracellular signaling pathways |
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Genetics of eye development and disease; mouse models |
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| Peter F. Hitchcock, Ph.D. | Neural stem cells, retinal growth and development, injury-induced neurogenesis and neuronal regeneration |
| Alon Kahana, M.D., Ph.D. | The biology and developmental genetics of extraocular muscles and neural crest-derived stem cells in the orbit and their importance in orbital cancer, craniofacial syndromes, congenital eye disorders and thyroid-related eye disease. |
| John R. Heckenlively, M.D. | Molecular identification of hereditary disease processes; autoimmune retinopathies; mouse models of eye diseases; phenotype-genotype correlations |
| Alon Kahana, M.D., Ph.D. | The biology and developmental genetics of neural crest-derived tissues in the orbit and their importance in orbital tumors and thyroid-related eye disease. |
| Sayoko E. Moroi, M.D., Ph.D. | Pharmacogenetics; genetics of glaucoma |
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Molecular genetic studies of glaucoma and other hereditary eye diseases; mapping of disease loci, positional candidate and candidate gene approaches to identification of disease genes, genotype-phenotype studies of glaucoma loci, expression profiling of ocular tissues; studies of primary open-angle glaucoma, secondary and developmental glaucomas, other traits such as nanophthalmos, corneal dystrophies, or syndromes associated with glaucoma |
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| Frank W. Rozsa, Ph.D. | Expression profile studies of trabecular meshwork and other cell types relevant to understanding loss of intraocular pressure homeostasis in glaucoma; studies of the role of differential gene expression events in glaucoma risk factors including aging |
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Molecular genetic studies of the role of defects in vitamin A metabolism as they relate to causes and treatment of retinal degeneration |
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| Neuroscience | |
| Jonathan B. Demb, Ph.D. | Visual information processing and the cellular basis for visual adaptation |
| Daniel G. Green, Ph.D. | Electrophysiology of normal and abnormal rodent retinas |
| Donald G. Puro, M.D., Ph.D. | Patch-clamp studies of retinal cells |
| Kwoon Y. Wong, Ph.D. | Retinal cells and circuits that regulate non-image-forming visual responses, such as the pupil reflex and the synchronization of the sleep-wake cycle with environmental light-dark cycles |
| Physiology and Biophysics | |
| Victor M. Elner, M.D., Ph.D. | Inflammatory and apoptotic processes of the eye; imaging of metabolism and cellular dysfunction of cells, animal models, and humans |
| Bret A. Hughes, Ph.D. | Function and regulation of ion channels and transporters in the retinal pigment epithelium |
| Howard R. Petty, Ph.D. |
Inflammatory processes within the eye; microscopic and other imaging techniques |
| Donald G. Puro, M.D., Ph.D. | Role of ion channels in retinal glial cell function |
| Vascular Biology | |
| Donald G. Puro, M.D., Ph.D. | Physiology and pathobiology of retinal microvessels; implications for diabetic retinopathy |
