April 10, 2008

Kellogg Eye Center at ARVO 2008

Over 50 research faculty and investigators from the University of Michigan Department of Ophthalmology and Visual Sciences will present papers or posters at the annual meeting of the Association for Research in Vision and Ophthalmology.  Abstracts and additional details are available at www.arvo.org

Educational Course

  • Course: Retinal Ganglion Cells in Model Organisms: Development, Function and Disease
    Saturday, April 26, 2008, 12:30 pm - 4:30 pm
    Functional Circuitry Of Visual Adaptation In The Retina
    Jonathan B. Demb.

Paper Session

  • Session: Corneal Transplantation: Penetrating and Lamellar Surgery
    Monday, April 28, 2008, 8:30 am - 10:15 am
    Design of Phase 2/3 Clinical Trials of a Cyclosporine A Eluting Implant, LX201, for the Prevention and Treatment of Corneal Allograft Rejection or Graft Failure in Patients at High Risk
    A. Sugar, Lux Corneal Transplant Implant Developmentand Advancement of Therapy Investigator Group.
  • Session: Photoreceptors and Phototransduction
    Tuesday, April 29, 2008, 8:30 am - 10:15 am
    Novel Ciliary Function for TOPORS Associated with Autosomal Dominant Retinitis Pigmentosa
    A.Z. Shah1, C. Chakarova1, H. Khanna, T. Sedmak2, M. Cheetham1, K. Matter1, U. Wolfrum2, R. Koenekoop3, A. Swaroop, S.S. Bhattacharya1.
    1Institute of Ophthalmology, London, United Kingdom; 2Johannes Gutenberg University of Mainz, Institute of Zoology, Mainz, Germany; 3McGill Ocular Genetics Laboratory, McGill University Health Centre, Montreal, QC, Canada.
  • Session: New Disease Genes, Loci and Phenotype-Genotype Correlations
    Tuesday, April 29, 2008, 3:00 pm - 4:45 pm
    Prevalence of Mutations in TOPORS Causing Autosomal Dominant Retinitis Pigmentosa (adRP)
    S.P. Daiger1, L.S. Sullivan1, A.I. Gire1, C.J. Spellicy1, D.G. Birch2, D. Hughbanks-Wheaton2, J.R. Heckenlively, S.J. Bowne1.
    1Human Genetics Center, School of Public Health, The University of Texas Health Science Center, Houston, TX; 2Retina Foundation of the Southwest, Dallas, TX.
  • Session: New Disease Genes, Loci and Phenotype-Genotype Correlations
    Tuesday, April 29, 2008, 3:00 pm - 4:45 pm
    Missense Mutations in RPGRIP1L Are Associated with Early-Onset Retinal Degeneration and Alter Its Interaction with RPGR and Selected NPHP and BBS Ciliary Proteins
    H. Khanna, A. Estrada, C. M-Zamalloa, I. Lopez1, N. Waseem2, A.I. den Hollander3, M.I. Othman, S.S. Bhattacharya2, R.K. Koenekoop1, A. Swaroop.
    1Ocular Genetics Laboratory, McGill University Health Centre, Montreal, QC, Canada; 2Ophthalmology, Institute of Ophthalmology, University College London, United Kingdom; 3Human Genetics, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.
  • Session: Retinal/RPE Degeneration and Repair
    Wednesday, April 30, 2008, 3:00 pm - 4:45 pm
    Antioxidant Treatment Rescues Oxidative Stress-Induced Photoreceptor Degeneration That Results from Intraretinal and Subretinal Neovascularization in vldlr-/- Mice
    M.I. Dorrell1, E. Aguilar1, R.A. Jacobson1, R. Gariano1, J. R. Heckenlively, E. Banin2, M. Friedlander1.
    1Cell Biology, The Scripps Research Institute, La Jolla, CA; 2Ophthalmology, Hadassah-Hebrew University, Jerusalem, Israel.
  • Session: Clinical Uveitis: Treatment and Assessment
    Thursday, May 1, 2008, 1:00 pm - 2:45 pm
    Retrospective Analysis of Treatment Results in Autoimmune Retinopathy
    J.R. Heckenlively, H. Ferreyra1, N.W. Khan, P. Titus, S. He, Y. Lu.
    1Ophthalmology & Visual Sciences, Shiley Eye Center, UCSD, San Diego, CA.

Poster Session

  • Session: Photoreceptor
    Sunday, April 27, 2008, 8:30 am - 10:15 am
    Identification of ARMS2/LOC387715 Domain Required for Localization to Mitochondrial Outer Membrane in Transfected Cells
    A. Kanda, A. Swaroop.
  • Session: Circadiam Rhythms: Cellular and Molecular Mechanisms
    Sunday, April 27, 2008, 8:30 am - 10:15 am
    P.F. Hitchcock, Moderator
  • Session: Circadiam Rhythms: Cellular and Molecular Mechanisms
    Sunday, April 27, 2008, 8:30 am - 10:15 am
    Expression of Midkine-a in Horizontal Cells Is Regulated by the Circadian Clock and May Modulate Circadian Neurogenesis in the Zebrafish Retina
    A. Calinescu1, P.F. Hitchcock.
    1Neuroscience, University of Michigan, Ann Arbor, MI.
  • Session: Age Related Macular Degeneration: Genetics I
    Sunday, April 27, 2008, 8:30 am - 10:15 am
    Late-Onset Severe Retinal Degeneration in a Mouse Model Due to a Nonsense Mutation
    V.R. Chavali, B. Chang1, M.N.A. Mandal, K. Yasumura, N. Hawes1, L. Kopplin2, B.E.K. Klein2, R. Klein2, J.R. Heckenlively, R. Ayyagari.
    1Jackson Laboratory, Bar Harbor, ME; 2Epidemiol & Biostatistics, Case Western Reserve Univ, Cleveland, OH.
  • Session: Clinical Autoinflammatory Disease
    Sunday, April 27, 2008, 2:30 pm - 4:15 pm
    Atypical Melanoma Associated Retinopathy
    D.M. Wu, Y. Lu, L. Jai, H. Khanna, M. Leys1, J.R. Heckenlively.
    1Ophthalmology, West Virginia University, Morgantown, WV.
  • Session: Regulation of VEGF in the RPE-choroidal Axis
    Sunday, April 27, 2008, 2:30 pm - 4:15 pm
    The MAP Kinase Pathway and VEGF are Involved in IGF-1-Stimulated Proliferation of Human Retinal Pigment Epithelial Cells (hRPE)
    C.Y. Weng, P.C. Kothary, M.A. Del Monte.
  • Session: Retinitis-Endophthalmitis
    Sunday, April 27, 2008, 2:30 pm - 4:15 pm
    Multiple Evanescent White Dot Syndrome in a Patient with Multifocal Choroiditis and Unilateral Hearing Loss
    S.M. Ronan1, A. Aizman, R.E. Hackel, S.J. Saxe.
    1Ophthalmology, Duke University Eye Center, Durham, NC.
  • Session: Retinitis-Endophthalmitis
    Sunday, April 27, 2008, 2:30 pm - 4:15 pm
    Incidence of Sterile Endophthalmitis Following Intravitreal Injection of Triamacinolone Acetonide
    H. Grabe, E.F. Hall, S.J. Saxe.
  • Session: Characterization of IOP
    Sunday, April 27, 2008, 2:30 pm - 4:15 pm
    Filtering Blebs with Microcysts and Less Vascularity Are Associated with Less Positional Intraocular Pressure Change
    P.A. Ple-plakon, J.S. Weizer, A. Goyal, A. Trzcinka, B.D. Strong, C.A. Bruno, J. Junn, I. Tseng, D.C. Musch, S.E. Moroi.
  • Session: Lasers and Seton Surgery
    Monday, April 28, 2008, 8:30 am - 10:15 am
    Outcomes of Surgical Revision of Glaucoma Drainage Devices for Tube Obstruction
    C.H. Choe, J.D. Stein, A.N. McCoy1, S. Asrani1, L.W. Herndon1, P.P. Lee1, S.J. McKinnon1, R.R. Allingham1, P. Challa1.
    1Ophthalmology, Duke University Medical Center, Durham, NC.
  • Session: Genetics II
    Monday, April 28, 2008, 8:30 am - 10:15 am
    Using Peripheral Blood Leukocytes to Detect PRPF31 Haploinsufficiency
    C
    .J. Spellicy1, S.J. Bowne1, L.S. Sullivan1, D. Hughbanks-Wheaton2, D.G. Birch2, J.R. Heckenlively, S.P. Daiger1.
    1Human Genetics Center, School of Public Health, The University of Texas Health Science Center, Houston, TX; 2Retina Foundation of the Southwest, Dallas, TX.
  • Session: AMD: Basic Mechanism
    Monday, April 28, 2008, 8:30 am - 10:15 am
    D.N. Zacks, Moderator
  • Session: Clinical Research: General
    Monday, April 28, 2008, 11:15 am - 1:00 pm
    Variations in Aqueous Humor Flow Response to Topical Beta-Blocker in Normal Humans
    A. Trzcinka, P.A. Radenbaugh, D.M. Reed, S.E. Moroi.
  • Session: Clinical Research: General
    Monday, April 28, 2008, 11:15 am - 1:00 pm
    The Effect of Early Postoperative IOP Spike on Visual Field Progression in the CIGTS
    P.P. Chen1, D.C. Musch, L.M. Niziol, CIGTS Study Group.
    1Ophthalmology, University of Washington, Seattle, WA.
  • Session: Genetics Group I
    Monday, April 28, 2008, 11:15 am - 1:00 pm
    Canine Rod Cone Dysplasia Type 2 (rcd2) Is the Canine Ortholog of Human and Murine RD3
    A.V. Kukekova1, O. Goldstein1, J.L. Johnson1, A. Swaroop, J.S. Friedman, G.D. Aguirre2, G.M. Acland1.
    1James A Baker Inst Animal Hlth, Cornell University, Ithaca, NY; 2School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA.
  • Session: Genetics Group I
    Monday, April 28, 2008, 11:15 am - 1:00 pm
    Clinical and Genetic Analysis of Inherited Developmental Abnormalities of the Eye and Orbit in a Large Family
    J.T. Pribila, S. Tarle1, C. Chou1, T. Glaser1, C.C. Nelson.
    1Internal Medicine and Human Genetics, University of Michigan, Ann Arbor, MI.
  • Session: Corneal Transplantation and Lamellar Surgery I
    Monday, April 28, 2008, 11:15 am - 1:00 pm
    Long-Term Outcomes in Patients Who Received a Corneal Graft for Keratoconus in 1980 to 1986
    D.C. Musch, L.M. Niziol, A. Sugar, H.K. Soong, S.I. Mian.
  • Session: Corneal Transplantation and Lamellar Surgery I
    Monday, April 28, 2008, 11:15 am - 1:00 pm
    Femtosecond Laser-Assisted Keratoplasty: Wound Shapes, Surgical Technique and Image Analysis in Eye Bank Globes
    J.B. Malta, M. Banitt, H. K. Soong, R. M. Shtein, D. C. Musch, A. Sugar, S. I. Mian.
  • Session: Retinal Dystrophy
    Monday, April 28, 2008, 3:00 pm - 4:45 pm
    Molecular Basis of Disease in Patients with Retinal Dystrophies
    H.V. Gudiseva, A.J. Karoukis, R. Aatre-Kesavamurthy, R.C. Caruso1, S. Periasamy2, I.M. MacDonald1, P. Sieving1, A. Villanueva3, J.R. Heckenlively, R. Ayyagari.
    1NEI/NIH, Bethesda, MD; 2Aravind Medical Research Foundation, Madurai, India; 3Virtual Eye Care, Mexico, Mexico.
  • Session: Microbiology and Infectious Disease III
    Tuesday, April 29, 2008, 8:30 am - 10:15 am
    Cytokine Profiles in Experimental Rabbit Models of Treated and Untreated Infectious Endophthalmitis
    E.F. Hall, D.M. Reed, D.N. Zacks.
  • Session: Retinal and Choroidal Angiogenesis II
    Tuesday, April 29, 2008, 8:30 am - 10:15 am
    Insulin Induced Angiogenic and Anti-Angiogenic Factor Synthesis in Human Retinal Pigment Epithelial Cells
    P.C. Kothary, M.A. Del Monte.
  • Session: Corneal Wound Healing and Cell Biology
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    Comparison of Wound Integrity of Clear Corneal Incisions Closed with Sutures, Fibrin Adhesive, or Cyanoacrylate Adhesive
    M. Banitt, J.B. Malta, H.K. Soong, S. I. Mian.
  • Session: Inherited Retinal Dystrophies, Retinal Cell Biology and Vitreous
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    Compound Heterozygous Inheritance of Best Vitelliform Macular Dystrophy
    T.R. Kinnick1, J.L. Andorf1, J.S. East1, M.E. Eyestone1, S.A. Mugge1, R.F. Mullins1, B.L. Lam2, J.R. Heckenlively, G.A. Fishman3, E.M. Stone4.
    1Department of Ophthalmology and Visual Sciences, Carver Family Center for Macular Degeneration, University of Iowa, Iowa City, IA; 2Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL; 3Department of Ophthalmology and Visual Sciences, University of Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL; 4Howard Hughes Medical Institute, Carver Family Center for Macular Degeneration, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA.
  • Retinal Diseases: Animal Models
    Session: Retinal Diseases: Animal Models
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    A New Mouse Model of a Late Onset Retinal Degeneration
    J. Wang1, N.L. Hawes1, C.C. Marden1, R.E. Hurd1, P. Ward-Bailey1, M.T. Davisson1, S. Nusinowitz2, J.R. Heckenlively, B. Chang1.
    1The Jackson Laboratories, Bar Harbor, ME; 2Department of Ophthalmology, Jules Stein Eye Institute, Los Angeles, CA.
  • Session: Eye Development/Gene Expression
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    A Regulatory Feedback Loop Including Dkk2 and Pitx2 Is Required for Normal Eye Development
    P.J. Gage, K.I. Rosenberg, D. Wu1, M. Qian.
    1Pharmacology, Yale University, New Haven, CT.
  • Session: Eye Development/Gene Expression
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    Progranulin-A Is a Microglia-Specific Growth Factor that Regulates Retinal Development and Photoreceptor Regeneration
    P.F. Hitchcock, T.S. Vihtelic1, D.R. Hyde1, L. Kakuk-Atkins.
    1Biological Sciences, University of Notre Dame, Notre Dame, IN.
  • Session: Eye Development/Gene Expression
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    Gene Profiling and Patterning in the Mouse Retina During Gestational Lead Exposure (GLE)
    A. Giddabasappa1, W. Xiao1, B. Xu1, S. Mukherjee1, S. Chaney1, M. Brooks, R. Khanna, A. Swaroop, D.A. Fox1.
    1University of Houston, Houston, TX.
  • Session: Eye Development/Gene Expression
    Tuesday, April 29, 2008, 11:15 am - 1:00 pm
    Gene Patterning and Genomic Location Analysis of Late-Born Retinal Cells in the Developing Mouse Retina
    W. Xiao1, A. Giddabasappa1, B. Xu1, S. Mukherjee1, M. Brooks, R. Khanna, A. Swaroop, D.A. Fox1.
    1University of Houston, Houston, TX.
  • Session: Visual Cycle, Binding Proteins and RPE Biochemistry
    Tuesday, April 29, 2008, 3:00 pm - 4:45 pm
    Retinoid Dehydrogenase/Reductase Activity and Expression in Rdh12 Knockout Mice
    J.D. Chrispell1, K.L. Feathers, I. Kurth2, A. Gal2, C. Hübner3, D.A. Thompson.
    1Biological Chemistry, University of Michigan, Ann Arbor, MI; 2University Medical Center Eppendorf, Institute of Human Genetics, Hamburg, Germany; 3Clinical Chemistry, Friedrich-Schiller-Universität Jena, Jena, Germany.
  • Session: Visual Cycle, Binding Proteins and RPE Biochemistry
    Tuesday, April 29, 2008, 3:00 pm - 4:45 pm
    The Role of Ras and Raf in FBS-Stimulated hRPE Cell Proliferation and VEGF Synthesis
    D.M. Louie, P.C. Kothary, M.A. Del Monte.
  • Session: RPE and Vascular Pathology
    Wednesday, April 30, 2008, 8:30 am - 10:15 am
    Topographical Distribution of Functional KATP Channels in the Rat Retinal Microvasculature
    E. Ishizaki, D.G. Puro.
  • Session: Basic and Clinical Genetics
    Thursday, May 1, 2008, 8:30 am - 10:15 am
    Sh3pxd2b Mutation Causes Anterior Segment Dysgenesis in Mice
    N.L. Hawes1, M. Mao2, B. Chang1, P. Fuerst1, R.S. Smith1,3, S.W.M. John1,3, J.R. Heckenlively, M.G. Anderson2, L. Donahue1.
    1The Jackson Laboratory, Bar Harbor, ME; 2Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA; 3Howard Hughes Medical Institute, Chevy Chase, MD.
  • Session: Retinal Detachment
    Thursday, May 1, 2008, 8:30 am - 10:15 am
    A New Mouse Model of a Retinal Detachment with Secondary Angle Closure Glaucoma
    B. Chang1, N.L. Hawes1, R.E. Hurd1, J. Wang1, M.T. Davisson1, S. Nusinowitz2, J.R. Heckenlively.
    1The Jackson Laboratory, Bar Harbor, ME; 2Department of Ophthalmology, Jules Stein Eye Institute, Los Angeles, CA.
  • Session: RPE Cell Biology in vitro and in vivo II
    Thursday, May 1, 2008, 10:45 am - 12:30 pm
    The MAP Kinase Inhibitor PD98059 Inhibits Proliferation and PEDF Production in hRPE Cells
    J.R. McManus1, P.C. Kothary, M.A. Del Monte.
    1University of Michigan Medical School, Ann Arbor, MI.
  • Session: Pterygium
    Thursday, May 1, 2008, 1:00 pm - 2:45 pm
    Efficacy of Subconjunctival Bevacizumab Injection in Primary and Recurrent Pterygia
    O.L. Lee1, M.R. Banitt, J.E. Anderson1, C.Y. Shih1, D.C. Ritterband1.
    1Ophthalmology, New York Eye and Ear Infirmary, New York, NY.
  • Session: Complex Genetics, Retinal Diseases, Linkage Analysis and Positional Cloning
    Thursday, May 1, 2008, 1:00 pm - 2:45 pm
    Genetic Modifiers of rd3 Retinal Degeneration
    M. Danciger1,2, D. Ogando1, H. Yang3, K.C. Ahern3, N. Akhmedov2, J.S. Friedman, A. Swaroop, R.W. Williams4, D.B. Farber2, M.M. LaVail3.
    1Biology, Loyola Marymount University, Los Angeles, CA; 2Jules Stein Eye Institute, UCLA, Los Angeles, CA; 3Beckman Vision Center, UCSF, San Francisco, CA; 4Anatomy and Neurobiology, University of Tennessee, Memphis, TN.
  • Session: Local Electroretinograms: Clinical
    Thursday, May 1, 2008, 1:00 pm - 2:45 pm
    Foveal Dystrophy or Dysfunction: A Clinical Entity
    N.W. Khan, J.R. Heckenlively.

Special Interest Group (SIG)

  • Complement Factor H and Age-related Macular Degeneration
    Sunday, April 27, 2008, 1:00 pm - 2:30 pm
    A. Swaroop, Moderator
  • Ciliary Proteins and Retinal Degeneration: New Perspectives and Future Directions
    Monday, April 28, 2008, 1:15 pm - 2:45 pm
    H. Khanna, SIG Organizer and Moderator

Symposia

  • Structural and Functional Consequences of Manipulating Synaptic Transmission
    Wednesday, April 30, 2008, 11:15 am - 1:00 pm
    A. Swaroop, Introduction - Manipulating Synaptic Input
Last Modified: Wednesday, 08-Feb-2012 10:23:26 EST