Hemant Khanna, Ph.D.
Lab Personnel
Stephen Atkins, B.S.
Amiya K. Ghosh, Ph.D.
Larry Koreen, M.D., M.P.H., Ph.D.
Carlos Murga-Zamalloa, M.D.
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Stephen Atkins, B.S.
Research Laboratory Specialist Associate
Ophthalmology and Visual Sciences
Fax: 734-647-0228
Email: sjatkins@med.umich.edu
Stephen received a Bachelors of Science degree from
In his spare time, Stephen enjoys studying history, watching Mythbusters, and reading classic science fiction.
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Amiya K. Ghosh, Ph.D.
Research Fellow
Ophthalmology and Visual Sciences
Phone: 734-936-8370
Fax: 734-647-0228
E-mail: amiyag@umich.edu
Dr. Ghosh received his Ph.D. from Bose Institute in Calcutta, India. His thesis focused on the protection and reversal of AZT-induced-hematopoietic toxicity by protein in mice.
Before coming to Kellogg, Dr. Ghosh had worked in the field of cell biology and signal transduction for more than five years. He was actively involved in delineating the role of Cbl family proteins in down-regulating activated receptor or non-receptor tyrosine kinases (RTK/NRTK) by proteosome/lysosomal degradation pathways. Overexpression or mutational activation of RTKs or NRTKs may lead to hyperproliferation and unregulated cellular growth resulting in cancer. Dr. Ghosh also contributed to the field of cancer therapy by studying the role of capsaicin, a natural compound found in chili peppers, in controlling tumor growth in mouse models as well as in vitro.
Dr. Ghosh joined the Khanna lab in April, 2008, where he studies retinitis pigmentosa. The retinitis pigmentosa 2 (RP2) gene is responsible for a particular variant of X-linked eye diseases. Mutations in RP2 cause X-linked retinitis pigmentosa. The functional importance of C-terminal NDK- (nucleoside diphosphate kinase) domain has not been explored; however, a pathogenic missense mutation of a residue conserved with NDK (L253R) has been reported. Much is known about its structural features and cellular localizations; however its RP2 function is not completely understood yet. Dr. Ghosh is currently exploring the functions of RP2 in the retina by utilizing genetic and biochemical techniques.
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Larry Koreen, M.D., M.P.H., Ph.D.
House Officer
Ophthalmology and Visual Sciences
Phone: 734-
Fax: 734-
E-mail: larrykor@umich.edu
Carlos Murga-Zamalloa, M.D.Research Fellow
Ophthalmology and Visual Sciences
Phone: (734) 936-8370
Fax: (734) 647-0228
Email: carlosmu@med.umich.edu
Carlos has an M.D. from San Martin de Porres University in Lima, Peru. While at the university, he performed clinical and genetic analysis of patients from Peruvian families with glaucoma who have mutations in different genes. His research resulted in a thesis entitled “Genetic Analysis of Peruvian Families Linked to the Locus GLC1B of Glaucoma.” He also has examined genetic diversity within Peruvian native populations.
Carlos joined the Khanna laboratory in September 2007. His research focuses on understanding the mechanism of X-linked retinitis pigmentosa due to mutations in the ciliary protein, retinitis pigmentosa GTPase regulator (RPGR). He is specifically involved in examining RPGR-interactome by analyzing protein-protein interactions, and characterizing of disease pathogenesis in mouse models with Rpgr mutations.
Carlos enjoys playing soccer and also plays the piano.
